US Congress · 119th Congress (2025-2026)

S 4472Passed Origin Chamber

Accelerating Access to Critical Therapies for ALS Reauthorization Act of 2026

Source of recordUS Congress · congress.govLast synced Aug 13, 2026

Chamber

Senate

Progress

Where this bill stands in the legislative process.

Introduced
Passed Senate
Passed House
To President
Became Law

Overview

This bill reauthorizes the Accelerating Access to Critical Therapies for ALS Act, extending its provisions through 2031. It makes several key changes to the program, including requiring the Food and Drug Administration to review the status of clinical trials for investigational ALS drugs and to publish a report on the agency’s plans for rare neurodegenerative diseases. The bill also extends the timeframe for the Government Accountability Office’s report on the Act’s implementation.

Key provisions

Extends the Accelerating Access to Critical Therapies for ALS Act through fiscal year 2031.
Requires the Secretary of Health and Human Services to assess the status of clinical trials when reviewing grant renewals for ALS therapies.
Mandates the sharing of interim clinical trial data from drug manufacturers with the FDA.
Expands the definition of ‘phase 3’ clinical trials to include combined phase 2/3 trials and planned phase 3 trials not yet enrolling participants.
Directs the FDA to publish a report on its action plan for rare neurodegenerative diseases, including updates to the 2022 Action Plan.
Extends the timeframe for the Government Accountability Office’s report on the Act’s implementation.
Specifies the reporting period for the GAO report to be 5 years after the enactment of the reauthorization act.

Who is affected

People with Amyotrophic Lateral Sclerosis (ALS)

Bill text

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Apr 30, 2026XMLView source

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Legislative history

11 recorded actions

Apr 30, 2026Senate

Read twice and referred to the Committee on Health, Education, Labor, and Pensions.

Apr 30, 2026

Introduced in Senate

Jun 17, 2026Senate

Committee on Health, Education, Labor, and Pensions. Ordered to be reported with an amendment in the nature of a substitute favorably.

Jul 16, 2026Senate

Placed on Senate Legislative Calendar under General Orders. Calendar No. 461.

Jul 16, 2026Senate

Committee on Health, Education, Labor, and Pensions. Reported by Senator Cassidy with an amendment in the nature of a substitute. Without written report.

Jul 16, 2026

Committee on Health, Education, Labor, and Pensions. Reported by Senator Cassidy with an amendment in the nature of a substitute. Without written report.

Aug 4, 2026Senate

Passed Senate with an amendment by Voice Vote. (consideration: CR S4425-4426; text: CR S4425-4426)

Aug 4, 2026

Passed/agreed to in Senate: Passed Senate with an amendment by Voice Vote.

Aug 10, 2026House

Held at the desk.

Aug 10, 2026House

Received in the House.

Aug 10, 2026Senate

Message on Senate action sent to the House.

Votes

Recorded roll calls and chamber actions on this bill.

Passage without roll call

The official record shows passage by unanimous consent or voice vote where no roll call was taken. No member-level tally is available for these steps, and the district map does not apply.

8/4/2026SenateVoice vote
Passed Senate with an amendment by Voice Vote. (consideration: CR S4425-4426; text: CR S4425-4426)
No roll-call vote on record for this action.
8/4/2026Voice vote
Passed/agreed to in Senate: Passed Senate with an amendment by Voice Vote.
No roll-call vote on record for this action.

Floor votes and chamber actions

Recorded roll calls list how each member voted. Unanimous consent or voice vote appears in the official action history without a roll call; no member-level tally is available for those steps.

Passage without roll call

Aug 4, 2026SenateVoice vote
Passed Senate with an amendment by Voice Vote. (consideration: CR S4425-4426; text: CR S4425-4426)
No roll-call vote on record for this action.
Aug 4, 2026Voice vote
Passed/agreed to in Senate: Passed Senate with an amendment by Voice Vote.
No roll-call vote on record for this action.

Geography

Recorded positions across the country.

No public positions recorded for this legislation.

Arguments

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Accelerating Access to Critical Therapies for ALS Reauthorization Act of 2026

Progress